Pigmentation Treatment
in Hyderabad

NCFT uses nano-crystalline tips to create precisely controlled microchannels across the skin surface, triggering controlled regeneration and dramatically enhancing the penetration of active brightening agents into the dermis. Unlike ablative lasers, NCFT carries no risk of post-procedure hyperpigmentation — making it particularly valuable for Fitzpatrick IV–VI skin where laser resurfacing carries PIH risk.

• Nano-crystalline tips create thousands of microchannels per cm², triggering a controlled wound-healing response that stimulates collagen production and skin renewal.
• Simultaneously, microchannels allow deep penetration of brightening actives (TXA, vitamin C, kojic acid, niacinamide) into the dermis at concentrations topical application cannot achieve.

• Melasma resistant to peels — mixed and dermal type
• Post-acne PIH with concurrent texture issues
• Dark Indian skin where laser carries PIH risk
• Patients wanting tone + texture improvement together

Exosome skin brightening uses nano-vesicles derived from mesenchymal stem cells to deliver growth factors, signalling proteins and skin-brightening peptides directly to melanocytes and keratinocytes. Exosomes modulate melanocyte behaviour at the cellular level — reducing aberrant melanin production, regulating melanocyte-stimulating signals and delivering antioxidant protection against UV-triggered melanin overproduction. Results improve progressively over 4–8 weeks.

• Highly purified exosomes are delivered into the skin dermis via micro-needling or the NCFT channel system — fusing with melanocytes and keratinocytes to deliver their brightening and regulatory cargo.
• Growth factors and signalling molecules modulate the melanin synthesis pathway, reducing tyrosinase activity and melanin transfer to keratinocytes — the fundamental mechanism driving pigmentation.

• Resistant melasma not responding to peels
• Dermal pigmentation with melanocyte dysregulation
• Combined with NCFT for maximum penetration
• Overall skin radiance and tone improvement

Tranexamic acid (TXA) is one of the most clinically robust pigmentation-correcting agents available — a pharmaceutical compound that inhibits the plasminogen-mediated pathway stimulating melanocyte production, directly suppressing the hormonal and inflammatory triggers driving melasma and PIH. When delivered via intradermal mesotherapy injection at dermatologist prescription, TXA reaches dermal melanocytes at concentrations that oral supplementation and topical application cannot achieve.

• TXA formulated with skin brightening co-actives (vitamin C, glutathione, niacinamide) is injected directly into the dermis via mesotherapy micro-injection across the pigmented zones.
• TXA suppresses the plasmin-mediated pathway that activates tyrosinase and melanocyte stimulation — directly reducing melanin production at the cellular level in both epidermal and dermal pigmentation.

• Melasma — hormonal and mixed type
• Deep dermal pigmentation
• Resistant pigmentation not responding to topicals
• Combined with FMS Peel Protocol or NCFT

The Q-Switched Nd:YAG laser is the gold standard for targeted pigmentation removal on Indian skin — delivering ultra-short nanosecond pulses at 1064nm (deep pigmentation) and 532nm KTP (superficial pigmentation) that selectively shatter melanin clusters without damaging surrounding tissue. Performed exclusively by board-certified dermatologists who calibrate wavelength, fluence and pulse duration for each patient’s specific pigmentation type and Fitzpatrick skin grade.
IMPORTANT: Q-Switched laser is NOT used for melasma on Indian skin — it can cause paradoxical darkening. Used for solar lentigines, freckles and discrete dark spots on eligible skin types only.

• Q-Switched laser fires energy in nanosecond bursts — creating a photoacoustic shockwave effect that shatters melanin granules into microscopic particles without generating significant thermal energy in surrounding tissue.
• The fragmented melanin particles are cleared by the body's lymphatic macrophages over 4-8 weeks. The 1064nm wavelength targets deeper, blue-grey pigmentation; the 532nm KTP targets superficial brown pigmentation and vascular components. Dermatologist selects wavelength based on pigmentation type and depth.

• Solar lentigines (age spots) and freckles
• Focal dark spots — selected eligible skin types
• Skin toning — generalised pigmentation reduction
• Post-acne PIH (epidermal — dermatologist selects)
• NOT used for melasma — can cause paradoxical darkening

Glutathione IV therapy delivers pharmaceutical-grade glutathione — the body’s master antioxidant and a proven inhibitor of the tyrosinase enzyme responsible for melanin synthesis — directly into the bloodstream at therapeutic concentrations oral supplementation cannot achieve. Glutathione suppresses melanin production systemically, shifting synthesis from dark eumelanin toward lighter phaeomelanin, producing progressive overall skin brightening.

• Pharmaceutical-grade glutathione is administered via IV infusion under dermatologist supervision — combined with Vitamin C (enhances anti-pigmentation activity), B-complex vitamins and skin-supportive micronutrients.
• Glutathione inhibits tyrosinase activity systemically and provides systemic antioxidant protection against UV-triggered melanin overproduction — addressing pigmentation from inside the body.

• Generalised uneven skin tone and dullness
• Overall skin brightening goals
• Systemic pigmentation support alongside topicals
• Patients with high UV exposure

Medical-grade chemical peels at FMS are clinician-applied treatments significantly more concentrated and effective than salon or at-home peels. FMS dermatologists use glycolic acid, lactic acid, salicylic acid, mandelic acid, modified Jessner’s solution, TCA and combination peels — selected specifically for each patient’s pigmentation type, skin type and Fitzpatrick grade. Never a single standard peel for every patient. Never applied without prior skin analysis.

• Peeling agents cause controlled exfoliation of pigmented epidermis — removing melanin-dense surface layers and stimulating growth of new, less-pigmented skin from below.
• For deeper (mixed/dermal) pigmentation, combination peels penetrate to the papillary dermis where melanophages containing trapped melanin are targeted. Post-peel brightening actives are applied for enhanced penetration.

• Sun tan removal — epidermal UV pigmentation
• Mild to moderate PIH
• Epidermal melasma
• Freckles and generalised uneven tone